Flamide (Nimesulide)

Active Ingredient: Nimesulide
Dosage: 100 mg
Route of Administration: Oral
Dosage Form: Tablets
Quantity per package: 10 tablets per pack
Availability: Out of stock

Flamide is a non-steroidal anti-inflammatory, selective inhibitor of cyclooxygenase 2. It is indicated for the suppression of inflammation, pain and fever caused by acute upper respiratory infections, primary dysmenorrhea, acute periods of rheumatic processes, sprains, strains, fractures, bursitis, postoperative processes, thrombophlebitis, gynecological disorders and disorders and dental maneuvers.

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Indications

The drug is indicated for the suppression of inflammation, pain and fever caused by acute upper respiratory infections, primary dysmenorrhea, acute periods of rheumatic processes, sprains, sprains, fractures, bursitis, post-surgical processes, thrombophlebitis, gynecological disorders and dental disorders and maneuvers.

Dosage and administration

Route of administration: Oral.

Dose: Adults: The recommended dose is one tablet every 12 hours that can be increased to two tablets every 12 hours depending on the symptomatology and the patient’s response. It is recommended to take the medication after meals. Dysmenorrhea: It is recommended to take one tablet every 12 hours for 10 days starting treatment five days before menstruation.

Contraindications

• Hypersensitivity to the active substance or to other non-steroidal anti-inflammatory drugs;
• Active gastrointestinal bleeding or gastroduodenal ulcer;
• Disorders of the heart, kidney, liver;
• Cytopenia;
• Severe arterial hypertension;
• Pregnancy and breastfeeding.

Side effects

Flamide tablets are well tolerated when used at the recommended doses. Occasionally, the drug can cause the following side effects: heartburn, nausea, vomiting, diarrhea and mild and transient gastralgias. Rare cases of allergic skin rash have been reported. It could also cause dizziness and drowsiness. In very rare cases, it caused liver abnormalities. In addition, the frequency of side effects increased when treatment was prolonged for more than 6-12 months; the main risk factor was the age of patients – older than 80 years), peripheral edema, stomatitis, paraesthesia, thrombocytopenic purpura, irritability, headache, and decreased visual acuity.

Overdose

In case of overdose, it is recommended to induce vomiting, gastric lavage and take activated carbon.

Interaction

The simultaneous use of nimesulide and other anticoagulant drugs increases the effect of the latter. The simultaneous administration of lithium with nimesulide causes an increase in plasma levels of the former. It can decrease the bioavailability of furosemide. It can significantly decrease the levels of theophylline in the plasma.