Eborix (Clebopride)

Active Ingredient: Clebopride
Dosage: 90 ml
Route of Administration: Oral
Dosage Form: Solution
Quantity per package: 1 unit
Availability: Out of stock

Eborix (clebopride) is a dopamine antagonist drug with antiemetic and prokinetic properties. It is used to treat functional gastrointestinal disorders such as nausea or vomiting.

Eborix is not available at the moment but you have a plenty of alternatives to choose from.

Indications

• Symptomatic treatment of nausea and vomiting;
• Functional disorders of digestive motility;
• Preparation in examinations of the digestive tract;
• Digestive disorders caused by radiotherapy, cobalt therapy and antineoplastic chemotherapy.

Dosage and administration

The drug is taken orally. Adolescents and young adults (between 12 and 20 years old): Half a tablet 3 times a day (before each meal). Adults (over 20 years old): Take 1 tablet 3 times a day (before each meal). In some cases, it may be recommended to reduce the dose by half.

Contraindications

• Patients whose stimulation of gastric motility may be harmful (bleeding, obstruction, perforation);
• Patients with proven delayed neuroleptic dyskinesia.

Side effects

If the recommended doses are exceeded, extrapyramidal reactions can occur with spasms of the muscles of the face, neck or tongue (in children). Methemoglobinemia may occur in newborns. It can also cause drowsiness or sedation. Older patients can experience undergoing late dyskinesias (with prolonged treatment). In prolonged treatments, hyperprolactinemia, breast tension, galactorrhea, amenorrhea, gynecomastia and / or impotence have been also observed.

Overdose

Overdose of Eborix may cause drowsiness, disorientation and extrapyramidal reactions that usually disappear when treatment is suspended. If symptoms persist, stomach lavage and symptomatic medication will be recommended. Extrapyramidal reactions are controlled with the administration of antiparkinsonians, anticholinergics or antihistamines with anticholinergic properties.

Interaction

Eborix potentiates the effects of phenothiazines and other antidopaminergics on the Central Nervous System. It decreases the effect of digoxin and cimetidine. Anticholinergics and narcotic analgesics neutralize its action in the digestive tract. Use with alcohol, tranquilizers, hypnotics or narcotics enhances the sedative effects.