Cefuracet (Cefuroxime)

Active Ingredient: Cefuroxime
Dosage: 250 mg/5 ml
Route of Administration: Oral
Dosage Form: Suspension
Quantity per package: 1 bottle
Availability: Out of stock

Cefuracet is used to treat a variety of bacterial infections. This drug is prescribed as a cephalosporin antibiotic. Its main function is to stop the growth of bacteria. It is prescribed for an oral administration. Currently, this drug and this release form are not available. Get acquainted with the antibiotic category to continue therapy.

Indications

Cefuracet is intended to treat infectious and inflammatory diseases caused by susceptible microorganisms:

• respiratory tract infections (including bronchitis, pneumonia, lung abscess, pleural empyema);
• infections of ENT organs (including sinusitis, tonsillitis, pharyngitis, otitis media);
• urinary tract infections (including pyelonephritis, cystitis, asymptomatic bacteriuria, gonorrhea);
• infections of the skin and soft tissues (including erysipelas, pyoderma, impetigo, furunculosis, phlegmon, erysipeloid);
• wound infection;
• infections of bones and joints (including osteomyelitis, septic arthritis);
• infections of the pelvic organs (endometritis, adnexitis, cervicitis);
• sepsis;
• meningitis;
• Lyme disease (borreliosis).
• Prevention of infectious complications during operations on the organs of the chest, abdominal cavity, pelvis, joints.

Dosage and administration

Pediatric suspension: children from 3 months to 12 years: It is preferable to adjust the dose according to age and weight.

Contraindications

Hypersensitivity to the drug and other cephalosporins, penicillins, and carbapenems.

The drug should be used in newborns and premature babies with caution in case of:

• chronic renal failure;
• bleeding and gastrointestinal diseases (including UC in history);
• during pregnancy and lactation;
• weakened patients’ condition.

Side effects

• Allergic reactions: chills, rash, itching, urticaria, rarely – erythema exsudativum multiforme, bronchospasm, malignant exudative erythema (Stevens-Johnson syndrome), anaphylactic shock.
• Digestive system: diarrhea, nausea, vomiting or constipation, flatulence, cramping, and abdominal pain, ulceration of the oral mucosa, candidiasis of the oral cavity, glossitis, pseudomembranous enterocolitis, impaired liver function, cholestasis.
• Urinary system: impaired renal function, dysuria.
• Reproductive system: itching in the perineum, vaginitis.
• Central nervous system: convulsions.
• Sensory organs: hearing loss.
• Hemopoietic system: a decrease in the concentration of hemoglobin and hematocrit, anemia (aplastic or hemolytic), eosinophilia, neutropenia, leukopenia, agranulocytosis, thrombocytopenia, hypoprothrombinemia, prolongation of prothrombin time.
• Local reactions: irritation, infiltration, and pain at the injection site, phlebitis.

Overdose

Symptoms: central nervous system agitation, convulsions.

Treatment: antiepileptic drugs, monitoring and maintaining vital body functions, hemodialysis, and peritoneal dialysis.

Interactions

The simultaneous oral administration of “loop” diuretics slows down tubular secretion, reduces renal clearance, increases plasma concentration and increases T1/2 of cefuroxime. Simultaneous use with aminoglycosides and diuretics, the risk of nephrotoxic effects increases.