Bonazin (Meclozine, Pyridoxine)

Active Ingredient: Meclozine, Pyridoxine
Dosage: 10 ml
Route of Administration: Oral
Dosage Form: Solution
Quantity per package: 1 unit
Availability: Out of stock

Bonazin relieves the symptoms of motion sickness. It helps relieve nausea and vomiting. Additionally, this medication is prescribed during toxicosis during pregnancy.

Bonazin is currently out of stock but you can order a similar medication for motion sickness here.

Indications

Bonazin is indicated for the prevention and symptomatic relief of nausea, vomiting and vertigo.

Dosage and administration

The drug is taken orally. Take Bonazin as directed by your doctor. Do not exceed the recommended doses.

To prevent motion sickness, take the solution about 1 hour before you travel or engage in activity that causes motion sickness. You may take the solution once every 24 hours while you are traveling.

To treat vertigo, take the drug several times daily.

Contraindications

The use of Bonazin is contraindicated when there is hypersensitivity to any of the components of the formula.

Side effects

The drug can cause drowsiness, dry mouth, fatigue, vomiting and blurred vision (rarely).

Overdose

Signs of overdose: In adults, the usual signs of Bonazin overdose are CNS depression, drowsiness, coma, and seizures. Hypotension may occur mainly in the elderly. In children, anticholinergic effects and stimulation of CNS are more likely (hallucinations, convulsions, restlessness).

Treatment of overdose: There is no specific antidote for the treatment of Bonazin overdose. Supportive measures and symptomatic treatment should be used. If the ingestion of the medicine is recent (up to an hour), vomiting should be induced or gastric lavage should be performed to empty the stomach if the patient has not vomited in the first three hours after ingestion. Activated carbon can also be used. The patient should be kept calm to reduce arousal. Vasopressors can be used to correct hypotension (norepinephrine or phenylephrine). Physostigmine may be useful to counteract the anticholinergic effects of meclozine on CNS. Do not use stimulants. If the use of vasopressors is indicated, do not apply epinephrine because it can cause hypotension.

Interaction

An increase in CNS depression may occur when Bonazin is administered simultaneously with other CNS depressants such as barbiturates, alcohol, tranquilizers and sedatives. Monoamine oxidase (MAO) inhibitors can prolong and intensify the anticholinergic effects of meclozine.